Fig. 4: Common genetic variants jointly associated with neuroticism (n = 432,109) and BMI (n = 184,305) at conjunctional false discovery rate (conjFDR) < 0.05. | Translational Psychiatry

Fig. 4: Common genetic variants jointly associated with neuroticism (n = 432,109) and BMI (n = 184,305) at conjunctional false discovery rate (conjFDR) < 0.05.

From: Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors

Fig. 4

Manhattan plot showing the –log10 transformed conjFDR values for each SNP on the y axis and the chromosomal positions along the x axis. The dotted horizontal line represents the threshold for significant shared associations (conjFDR < 0.05, i.e., −log10(conjFDR) > 2.0). Independent lead SNPs are encircled in black. The significant shared signal in the major histocompatibility complex region (chr6:25119106–33854733) is represented by one independent lead SNP. Further details are available in Supplementary Table 3.

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