Fig. 1: Overall downstream informatics workflow and symptom analysis. | Translational Psychiatry

Fig. 1: Overall downstream informatics workflow and symptom analysis.

From: Teasing apart trauma: neural oscillations differentiate individual cases of mild traumatic brain injury from post-traumatic stress disorder even when symptoms overlap

Fig. 1

A A flowchart showing overall downstream informatics analysis workflow. B Concussion, anxiety and depression symptom profiles overlap in PTSD and mTBI. Rain cloud plots showing mTBI symptom number, mTBI severity, anxiety and depression score for the mTBI, PTSD, TC and NTC groups. Raw data (dots), boxplot and probability distribution are plotted. No statistical difference was observed for PTSD and mTBI in mTBI symptoms. PTSD participants (without head injury) reported significantly higher mTBI symptom severity than the mTBI participants. Although PTSD participants exhibited significantly higher anxiety and depression scores than the mTBI participants, both PTSD and mTBI groups scored significantly higher than both controls groups in the two scales. *=statistically significant (p < 0.05) differences based on the ANOVA with Tukey post-hoc test. FDR false discovery rate, CV-SVM-rRF-FS support vector machine and recursive random forest feature selection with cross validation, PLS-DA partial least squares discriminate analysis, NTC non-trauma control, TC trauma-exposed control, SCAT2 Sports Concussion Assessment Tool 2, GAD-7 Generalised Anxiety Disorder 7, PHQ-9 Patient Health Questionnaire.

Back to article page