Fig. 3: Effect of ibudilast on alcohol cue-induced activation in the ventral striatum. | Translational Psychiatry

Fig. 3: Effect of ibudilast on alcohol cue-induced activation in the ventral striatum.

From: Ibudilast, a neuroimmune modulator, reduces heavy drinking and alcohol cue-elicited neural activation: a randomized trial

Fig. 3

A IBUD attenuated the percent signal change to alcohol vs. beverage cues as compared to placebo (p = 0.01). B Medication by ventral striatal activation interaction. There was a significant medication by striatal activation (median split) interaction (p = 0.01). Individuals treated with IBUD who showed attenuated ventral striatal activation to alcohol cues had the fewest drinks per drinking day in the week following the fMRI scan.

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