Table 1 Sample characteristics at baseline by treatment condition.
Variable | Ibudilast (n = 24) | Placebo (n = 28) |
|---|---|---|
Demographics | ||
Age | 34.46 ± 9.24 | 31.07 ± 7.81 |
Sex, No. (%) | ||
Male | 16 (66.7%) | 18 (64.3%) |
Female | 8 (33.3%) | 10 (35.7%) |
Race/Ethnicity, No (%) | ||
White | 17 (70.8%) | 12 (42.9%) |
African American | 5 (20.8%) | 2 (7.1%) |
Asian | 0 (0%) | 5 (17.9%) |
Pacific Islander | 0 (0%) | 1 (3.6%) |
Mixed Race | 1 (4.2%) | 5 (17.9%) |
Another Race | 1 (4.2%) | 3 (10.7%) |
Hispanic or Latino | 5 (20.8%) | 7 (25%) |
Years of Education | 15.21 ± 2.64 | 15.21 ± 1.75 |
Drinking characteristics | ||
Withdrawal-related dysphoria (Y/N)a | 9/15 | 11/17 |
AUD symptom count | 5.29 ± 2.37 | 4.86 ± 2.27 |
AUDIT total score | 16.38 ± 5.90 | 16.71 ± 6.42 |
ADS total score | 13.00 ± 6.10 | 12.07 ± 7.01 |
PACS total score | 12.79 ± 1 5.14 | 12.11 ± 7.04 |
OCDS total | 14.54 ± 6.05 | 13.93 ± 8.07 |
RHDQ – reinforcing | 23.29 ± 3.51 | 22.82 ± 4.88 |
RHDQ – normalizing | 9.67 ± 7.1 | 8.29 ± 7.34 |
Total drinks (30 days)b | 122.89 ± 64.58 | 114.119 ± 108.72 |
Drinking days (30 days)b | 22.21 ± 6.87 | 20.25 ± 6.51 |
Drinks per day (30 days)b | 4.10 ± 2.15 | 3.81 ± 3.62 |
Drinks per drinking days (30 days)b | 5.70 ± 2.58 | 5.34 ± 3.57 |
Heavy drinking days (30 days)b | 10.79 ± 8.29 | 8.68 ± 8.04 |
Cigarette and cannabis characteristics | ||
Cigarette smokers (%) | 11 (45.8%) | 14 (50%) |
FTND score | 2.82 ± 2.82 | 1.07 ± 1.54 |
Total cigarettes (30 days)b | 52.28 ± 79.85 | 133.07 ± 205.78 |
Cigarettes per day (30 days)b | 7.39 ± 8.70 | 5.06 ± 6.76 |
THC + urine (Y/N) | 7/17 | 8/20 |
Cannabis days (30 days)b | 11.38 ± 9.99 (n = 13) | 8.15 ± 8.24(n = 13) |
Other characteristics | ||
BDI-II total score | 12.42 ± 8.47 | 8.64 ± 7.82 |
