Table 2 Effect of ibudilast on heavy drinking and craving.
Model and predictor variables | Parameter estimate | SE | 95% confidence limits | Odds ratio | 95% confidence limits | ||||
|---|---|---|---|---|---|---|---|---|---|
LL | UL | Z | P | LL | UL | ||||
Negative mood (POMS) | |||||||||
Medication (IBUD) | 0.34 | 0.69 | −1.01 | 1.69 | 0.49 | 0.62 | |||
Drinking day (no) | −0.13 | 0.18 | −0.48 | 0.22 | −0.74 | 0.46 | |||
Med X drinking day | 0.21 | 0.49 | −0.76 | −0.48 | 0.42 | 9.67 | |||
Heavy drinking | |||||||||
Medication (IBUD) | −0.60 | 0.30 | −1.19 | −0.02 | −2.02 | 0.04 | 0.55 | 0.30 | 0.98 |
Time | 0.003 | 0.02 | −0.04 | 0.04 | 0.16 | 0.87 | 1.00 | 0.96 | 1.04 |
Smoking status (nonsmoker) | −0.87 | 0.32 | −1.50 | −0.24 | −2.71 | 0.007 | 0.42 | 0.22 | 0.79 |
Baseline HDD | 0.08 | 0.03 | 0.03 | 0.13 | 2.99 | 0.003 | 1.08 | 1.03 | 1.14 |
Craving (AUQ) | |||||||||
Medication (IBUD) | −0.16 | 0.76 | −1.62 | 1.30 | −0.21 | 0.83 | |||
Drinking day (no) | −1.06 | 0.28 | −1.61 | −0.50 | −3.75 | <0.001 | |||
Med X Drinking Day | −0.90 | 0.49 | −1.86 | 0.06 | −1.84 | 0.07 | |||
