Table 1 Clinico-demographic and imaging variables in healthy volunteer (HV) and schizophrenia (SCZ) groups. Values are mean (SEM) or number (n).

From: The relationship between synaptic density marker SV2A, glutamate and N-acetyl aspartate levels in healthy volunteers and schizophrenia: a multimodal PET and magnetic resonance spectroscopy brain imaging study

 

HV

SCZ

t

Kolmogorov-Smirnov D

Chi-square

df

p

Age (years)

38.23 [2.59]

40.89 [2.75]

0.25

0.55

Male; Female (n)

21; 1

15; 3

1.62

0.20

Ethnicity

White; black; other (n)

9; 9; 4

3; 13; 2

4.03

2

0.13

Current smoker (n)

3

12

11.88

1

0.0006

Cannabis use within last month (n)

0

2

2.57

1

0.11

Activity injected

264.40 [5.62]

243.60 [10.88]

0.32

0.25

Plasma free fraction

0.24 [0.005]

0.24 [0.005]

0.82

38.0

0.42

CS

[11C]UCB-J VT

5.62 [0.12]

5.92 [0.34]

0.91

38.0

0.37

ACC

[11C]UCB-J DVR

3.95 [0.10]

3.48 [0.18]

2.38

38.0

0.02

[11C]UCB-J VT

22.08 [0.67]

19.19 [0.76]

2.87

38.0

0.007

Glu/Cr

1.10 [0.02]

1.06 [0.02]

1.35

38.0

0.19

Glx/Cr

1.29 [0.03]

1.31 [0.05]

0.31

38.0

0.75

NAA/Cr

1.13 [0.02]

1.14 [0.02]

0.04

38.0

0.97

Left hippocampus

[11C]UCB-J DVR

2.67 [0.08]

2.46 [0.14]

1.42

38.0

0.17

[11C]UCB-J VT

14.92 [0.50]

14.17 [0.54]

1.00

38.0

0.32

Glu/Cr

0.97 [0.03]

0.93 [0.04]

0.78

37.0

0.44

Glx/Cr

1.38 [0.06]

1.28 [0.07]

1.03

37.0

0.31

NAA/Cr

1.10 [0.03]

1.07 [0.04]

0.71

37.0

0.48