Table 1 Sociodemographic and clinical differences between genotyped and not-genotyped individuals.
Case/control sample N = 2627 | GWAS—NO | GWAS—YES | Test statistics |
|---|---|---|---|
N = 556 | N = 2,071 | ||
(NFEP = 1130, Ncontrols = 1497) | (NFEP = 282, Ncontrols = 274) | (NFEP = 856, Ncontrols = 1215) | |
Case/control status | |||
Case | 274 (49.3) | 856 (41.3) | χ2 (1) = 11.3; p = 0.001 |
Age | |||
Mean (SD) | 32.6 (11.5) | 34.3 (12.4) | t(2,2642) = 2.9; p < 0.05 |
Gender | |||
Male | 299 (53.8) | 1104 (53.3) | χ2 (1) = 0.03; p = 0.84 |
Self-reported Ethnicity | |||
White | 374 (67.3) | 1520 (73.4) | χ2 (5 )= 8.5; p = 0.13 |
Black | 78 (14) | 226 (10.9) | |
Mixed | 54 (9.7) | 172 (8.3) | |
Asian | 17 (3.1) | 51 (2.5) | |
North African | 19 (3.4) | 57 (2.7) | |
Other | 14 (2.5) | 45 (2.2) | |
Country | |||
United Kingdom | 123 (22.1) | 459 (22.2) | χ2 (5) = 78.7; p < 0.001 |
Holland | 54 (9.7) | 352 (17) | |
Spain | 74 (13.3) | 352 (17) | |
France | 71 (12.8) | 181 (8.7) | |
Italy | 157 (28.2) | 310 (15) | |
Brazil | 77 (13.8) | 417 (20.1) | |
Research Domain Criteria Diagnosis (case only sample) | |||
Bipolar disorder | 13 (4.7) | 47 (5.5) | χ2 (4) = 3.3; p = 0.5 |
Major depression with psychotic features | 18 (5.9) | 32 (4) | |
Schizophrenia | 84 (30.7) | 306 (35.7) | |
Schizoaffective disorder | 116 (42.3) | 318 (37.1) | |
Unspecified psychosis | 48 (17.5) | 148 (17.3) | |
