Fig. 3: Increase in functional connectivity between the hippocampus and striatum in the propranolol group during the reconsolidation process.

A, B The hippocampus as the region of interest and brain regions that showed an increase in connectivity with the hippocampus in the propranolol group during the second resting-state fMRI scan. C Propranolol administration significantly decreased heart rate. D Functional connectivity between the hippocampus and striatum negatively correlated with craving scores on day 3 in the propranolol group. No significant correlation was detected in the placebo group.