Table 2 Clusters that showed a significant increase in activation in response to smoking-related cues at baseline (smoking-related cues > neutral cues).

From: Neural substrates of propranolol-induced impairments in the reconsolidation of nicotine-associated memories in smokers

Anatomical region

Coordinates

T

Cluster size (no. of voxels)

Hemisphere

X

Y

Z

Midbrain subthalamic nucleus (caudate)

−9

−8

−3

3.14

125

L

Postcentral gyrus

48

−20

44

2.94

140

R

Declive

48

−49

–21

3.45

140

R

Inferior semi-lunar lobule

−24

−61

−42

3.2

41

L

  1. Coordinates are given for the maximally significant voxel in each area, where X defines the lateral placement from the midline (left = negative), Y defines the anteroposterior displacement relative to the anterior commissure (posterior = negative), and Z defines the vertical position relative to the anteroposterior commissural line (down = negative). P values were corrected for multiple comparisons at P < 0.001 (Monte Carlo simulations using AlphaSim were used to calculate the minimum cluster size at an uncorrected threshold of P < 0.001 required for a whole-brain correction of P < 0.05. Simulations (1000 iterations) were performed and resulting in a minimum cluster size of 38 contiguous voxels.). The coordinates are in Montreal Neurological Institute (MNI) space. The brain regions were automatically identified by NeuroElf software.
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