Fig. 1: Genome-wide genetic overlap between risk phenotypes, bipolar disorder and schizophrenia.
From: Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
MiXeR analysis for a bipolar disorder (BIP) and risk-taking, b BIP and risky behaviours, c schizophrenia (SCZ) and risk-taking, and d SCZ and risky behaviours. Venn diagrams representing the unique and shared variants associated with risk-taking and risky behaviours and each of SCZ and BIP. Polygenic overlap is represented in grey, Risk/risky behaviours in blue and BIP/SCZ in orange. The numbers indicate the estimated quantity of variants in thousands per component that explains 90% of SNP heritability for each phenotype (standard error in parentheses). The size of the circle reflects the extent of polygenicity for each trait.
