Fig. 6: Bilobalide reduces amyloid and inflammation in AD mouse brain. | Translational Psychiatry

Fig. 6: Bilobalide reduces amyloid and inflammation in AD mouse brain.

From: Bilobalide inhibits inflammation and promotes the expression of Aβ degrading enzymes in astrocytes to rescue neuronal deficiency in AD models

Fig. 6

A ELISA results showing Aβ42 and Aβ40 levels in the brain lysates of APP/PS1 mice treated with DMSO (n = 6) or Bilobalide (n = 6). B ELISA results showing TNF-α, IL-1β, and IL-6 levels in the brain lysates of APP/PS1 mice treated with DMSO (n = 6) or Bilobalide (n = 6). C Western blot and its quantification showing the protein levels of NEP, IDE, MMP2, and STAT3 in the brain lysates of APP/PS1 mice treated with DMSO (n = 6) or Bilobalide (n = 6). D Western blot and its quantification showing the protein levels of PSD-95, Synapsin-1, and GluR1 in the brain lysates of APP/PS1 mice treated with DMSO (n = 6) or Bilobalide (n = 6). **P < 0.01.

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