Fig. 3: Symptom-, clinical-, and cytokine profiles of individuals with symptom-specific autoantibodies.
From: Autoantibody profiles associated with clinical features in psychotic disorders
A We found six autoantibodies with high specificity for past or current psychiatric symptoms and meeting selection criteria for group size (n ≥ 10), symptom prevalence (symptom present in >85% of seropositive individuals) and symptom prevalence ratio (>25% higher symptom prevalence in seropositive individuals). B Some of these symptom-specific autoantibodies were associated with additional clinical and biological features. Bars indicate prevalence of the feature in the seropositive and seronegative groups for the present autoantibody. Dots and confidence intervals indicate odds ratio of the seropositive group. Percentages are within the seropositive/seronegative groups. Half diamonds indicate zero. Half squares indicate infinity. DSCT score median: 39. IL-4 and IL-6 medians: <1 fg/mL. IL-8 median: 3.6 pg/mL. Cu, Zn-SOD median: 333 ng/mL. AP3B2 AP-3 complex subunit beta-2, TDO2 Tryptophan 2,3-dioxygenase, CRYGN Gamma-crystallin N, APMAP Adipocyte plasma membrane-associated protein, OLFM1 Noelin, WHAMMP3 Putative WASP homolog-associated protein with actin, membranes, and microtubules-like protein 1, Pos seropositive individuals, Neg seronegative individuals, IL-4 Interleukin 4, IL-6 Interleukin 6, IL-8 Interleukin 8, IL-10 Interleukin 10, Cu, Zn-SOD, Cu, Zn superoxide dismutase.
