Table 2 Reasons for exclusion of participants.

Site	Initial number of images	QC (visual or auto)	Freesurfer failed	Subfield analysis failed	Not in covariates file	“Patients” without GAD^a	“HC” with other disorder^b	Comorbid psychosis	Missing age	Missing MDD, OCD, PTSD and SUD	Missing IQ and/or Edu	Participants in main analysis	Participants in secondary analysis
ABCD	1600	140	2	2	0	0	0	0	5	0	0	1451	1451
Barcelona	91	0	0	0	0	0	1	0	0	0	1	89	89
Baylor	228	0	0	0	0	0	0	0	0	0	0	228	228
BHRCS	781^c	238	1	0	5	58	84	0	0	0	7	388	388
Boystown	95	1	0	0	0	0	1	0	0	0	0	93	93
Chicago-Milad	43	0	0	0	0	0	0	0	0	0	0	43	43
Chicago-Phan	147	3	0	0	0	24	0	0	0	0	0	120	120
Cincinnati	21	16	0	0	0	0	2	0	0	0	0	–	3
CMI-HBN	290	48	11	0	0	0	0	0	0	0	138	93	93
Dresden	94	0	0	0	0	0	0	0	0	0	0	94	94
Duke	45	20	0	0	0	2	0	0	0	0	0	23	23
Harvard	260	38	0	0	0	57	0	0	0	0	2	163	163
Houston	273	63	3	0	0	0	0	0	0	0	17	–	190
IOL	64	16	0	0	0	7	0	0	0	0	1	40	40
Milan	98	1	0	0	0	0	2	0	0	0	28	67	67
Muenster	54	0	0	0	0	0	0	0	0	0	1	53	53
Pittsburgh- Andreescu	79	16	0	0	0	0	0	0	0	0	4	59	59
Pittsburgh-Price	69	0	0	0	0	11	0	0	0	0	3	–	55
PROTAIA	44	6	0	0	0	5	9	1	0	0	9	–	14
SanRaffaele	92	0	1	0	0	0	0	0	0	0	0	–	91
SDAN	406	28	0	0	0	0	0	0	0	0	11	367	367
SHIP	36	0	0	0	0	0	0	0	0	2	0	36	34
SNFA	63	25	0	0	0	2	0	0	0	0	12	–	24
StonyBrook	61	0	1	0	0	0	0	0	0	0	0	60	60
Sussex	40	0	0	0	0	0	0	0	0	0	0	40	40
UCSD	96	6	0	0	0	0	0	0	0	0	6	84	84
UPenn	455	61	0	0	0	0	0	13	0	0	0	381	381
WashU	63	6	0	0	0	7	3	0	0	0	0	47	47
Total	5688	732	19	2	5	173	100	14	5	2	240	4019	4394

QC quality checking, auto automated, GAD generalized anxiety disorder, HC healthy controls, MDD major depressive disorder, OCD obsessive-compulsive disorder, PTSD post-traumatic stress disorder, SUD substance use dependence, Edu education in years, ABCD Adolescent Brain Cognitive Development Study, BHRCS Brazilian High Risk Cohort Study, CMI-HBN Child Mind Institute Healthy Brain Network, IOL Institute of Living, PROTAIA Anxiety Disorders Program for Child and Adolescent Psychiatry, SDAN Section on Development and Affective Neuroscience, SHIP Study of Health in Pomerania, SNFA Section on Neurobiology of Fear and Anxiety, UCSD University of California – San Diego, UPenn University of Pennsylvania, WashU Washington University.
^aThese participants were classified as patients in the “number of images of high quality” in Table 1, but did not have a GAD diagnosis.
^bFor 12 participants in the initial number of images there were no behavioral data available, 5 of these participants had images of high quality.
^cThese participants were classified as HC in the “number of images of high quality” in Table 1, but had a diagnosis other than GAD.

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