Table 3 The negative/positive valence systems and cognitive systems.

From: Understanding complex functional wiring patterns in major depressive disorder through brain functional connectome

Systems

Behavior

Brain Circuits

Function

Negative valence systems

Threat (acute/potential); loss; frustration

Amygdala; hippocampus; insula; ACC; lateral PFC

Facial emotion identification

Positive valence systems

Reward (Responsiveness; learning; valuation)

Striatum; OFC; vmPFC; ACC

Positive emotion reactivity; reward responsiveness; reward learning

Cognitive systems

Working memory; cognitive control

DLPFC, DPC, precentral gyrus

Memory performance; concentration; impulsive behavior; speed of information processing; attention

  1. ACC Anterior cingulate cortex, PFC Prefrontal cortex, OFC Orbitofrontal cortex, vmPFC Ventromedial prefrontal cortex, DLPFC Dorsolateral prefrontal cortex, PCC Posterior cingulate cortex, AG Angular gyrus, amPFC Anterior medial prefrontal cortex, DPC Dorsal parietal cortex.
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