Fig. 2: Increased frequency and amplitude of mEPSCs in iPSC-derived neurons from patients. | Translational Psychiatry

Fig. 2: Increased frequency and amplitude of mEPSCs in iPSC-derived neurons from patients.

From: Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia

Fig. 2

A Representative traces of mEPSCs obtained from iPSC-derived neurons from controls and patients. B Cumulative probability plot showing a significant shift of the distribution of inter-event interval toward shorter intervals in iPSC-derived neurons from patients. C Cumulative probability plot showing a significant shift of the distribution of amplitude toward a larger amplitude in iPSC-derived neurons from patients. P < 0.001, Kormogorov–Smirnov test. Data were presented as mean ± standard error of the mean (SEM).

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