Fig. 2: Protein expression profile.
From: Proteomics analysis of the gut–brain axis in a gut microbiota-dysbiosis model of depression
A Donut plots represent the percentages of cellular compartments of all proteins. B Composition of the functional groups annotated by IPA. In the PFC, about 2.1% of proteins involved in ion channel functions, which was approximately twice as high as that in the liver, cecum, and serum. The proportion of G protein-coupled receptors in the PFC was also three times higher than that in the cecum and liver. In the serum, the numbers of growth factors, cytokines, transmembrane receptors, and peptidases were markedly higher than that in the other three tissues. C Union heatmaps show fold changes of all proteins for the gut–brain axis of FMT model, the PFC of CSDS model, and the liver of CUMS model.
