Fig. 1: Hibar et al. [26] GWAS hippocampal polygenic score (PGS).

The significance (A) and effect size estimate (B) of the PGS predicting hippocampal volume as a function of the significance threshold. Meta meta-analysis, PGC-PTSD Psychiatric Genetics Consortium-Posttraumatic Stress Disorder, TRAC Translational Research Center for TBI and Stress, VETS Vietnam Era Twin Study of Aging; MIRE MIRE = Duke University and VA Mid-Atlantic Mental Illness Research Education and Clinical Center, UKBB United Kingdom BioBank.