Fig. 2: Forest plots of the effect of the GxE interaction between hippocampal polygenic score (PGS) and PTSD its effect on hippocampal volume.

Both the PGS and volumes have been standardized (mean = 0, SD = 1). (Meta meta-analysis, PGC-PTSD Psychiatric Genetics Consortium-Posttraumatic Stress Disorder, TRAC Translational Research Center for TBI and Stress, VETS Vietnam Era Twin Study of Aging; MIRE MIRE = Duke University and VA Mid-Atlantic Mental Illness Research Education and Clinical Center, UKBB United Kingdom BioBank).