Table 1 Demographic and epidemiological description of the cohort.
Variables | N total | Mean | SD |
|---|---|---|---|
Average age at the time of the LP (years ± SD) | 331 | 37.67 | 15.58 |
N total | Frequency | ||
Gender (female/male) | 331 | 143/188 | |
A family history of psychiatric disorders | 315 | 147/315 (46.7%) | |
Illegal substance abuse | 324 | 79/324 (24.4%) | |
Alcohol abuse | 322 | 74/322 (23%) | |
Cannabis abuse | 324 | 81/324 (25%) | |
Tobacco abuse | 322 | 148/322 (46%) | |
Diagnosed with rheumatic, infectious, oncologic, or CNS disease | 329 | 63/329 (19.1%) | |
Diabetes type II | 328 | 18/328 (5.5%) | |
Thyroid disease | 329 | 45/329 (13.7%) | |
N total | Mean | SD | |
Duration of illness at the time of the LP (months ± SD) | 277 | 71.96 | 102.59 |
N total | Frequency | ||
FEP at time of LP | 320 | 128/320 (40%) | |
Recurrent psychotic episode | 320 | 192/320 (60%) | |
Clozapine lifetime treatment | 331 | 68/331 (20.5%) | |
Any cMRI alteration(s) | 313 | 173/313 (55.3%) | |
White matter lesion | 313 | 109/313 (34.8%) | |
Atrophy | 313 | 24/313 (7.7%) | |
Tumor | 313 | 11/313 (3.5%) | |
Other | 313 | 91/313 (29.1%) |