Table 1 Demographic and epidemiological description of the cohort.

From: Cerebrospinal fluid abnormalities in first- and multi-episode schizophrenia-spectrum disorders: impact of clinical and demographical variables

Variables

N total

Mean

SD

Average age at the time of the LP (years ± SD)

331

37.67

15.58

 

N total

Frequency

 

Gender (female/male)

331

143/188

 

A family history of psychiatric disorders

315

147/315 (46.7%)

 

Illegal substance abuse

324

79/324 (24.4%)

 

Alcohol abuse

322

74/322 (23%)

 

Cannabis abuse

324

81/324 (25%)

 

Tobacco abuse

322

148/322 (46%)

 

Diagnosed with rheumatic, infectious, oncologic, or CNS disease

329

63/329 (19.1%)

 

Diabetes type II

328

18/328 (5.5%)

 

Thyroid disease

329

45/329 (13.7%)

 
 

N total

Mean

SD

Duration of illness at the time of the LP (months ± SD)

277

71.96

102.59

 

N total

Frequency

 

FEP at time of LP

320

128/320 (40%)

 

Recurrent psychotic episode

320

192/320 (60%)

 

Clozapine lifetime treatment

331

68/331 (20.5%)

 

Any cMRI alteration(s)

313

173/313 (55.3%)

 

White matter lesion

313

109/313 (34.8%)

 

Atrophy

313

24/313 (7.7%)

 

Tumor

313

11/313 (3.5%)

 

Other

313

91/313 (29.1%)

 
  1. cMRI cerebal magnetic resonance imaging, CNS central nervous system, FEP first-episode psychosis, LP lumbar puncture, SD standard deviation.