Table 2 Correlations between age and post-surgery DNAm in the TNF gene.

From: DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium

		EPIC		EPIC		EPIC		pyrosequencing		pyrosequencing		pyrosequencing
		all		POD		non-POD		all		POD		non-POD
		N = 37		N = 10		N = 27		N = 27		N = 7		N = 20
cg	location	r	p	r	p	r	p	r	p	r	p	r	p
	chr6: 31542460							0.09	0.67	0.01	0.98	0.13	0.60
cg08639424	chr6: 31542556	−0.03	0.84	−0.50	0.14	−0.08	0.69
cg19978379	chr6: 31542671	0.17	0.33	−0.14	0.70	0.19	0.34
cg24452282	chr6: 31542741	0.19	0.25	0.00	0.99	0.17	0.40
	chr6: 31543170							−0.33	0.10	−0.44	0.32	−0.54	0.01
	chr6: 31543176							–0.43	0.02	-0.33	0.47	−0.53	0.02
	chr6: 31543178							−0.21	0.29	−0.08	0.87	−0.22	0.34
	chr6: 31543193							−0.49	0.01	−0.61	0.14	−0.45	0.046
cg21370522	chr6: 31543219	0.26	0.13	0.23	0.51	0.28	0.16	−0.34	0.08	−0.44	0.32	−0.46	0.04
cg19648923	chr6: 31543266	0.00	0.98	0.00	0.99	0.02	0.91	−0.26	0.18	−0.39	0.39	−0.33	0.16
cg01569083	chr6: 31543290	0.06	0.71	−0.09	0.80	0.18	0.36	−0.47	0.01	−0.30	0.51	−0.55	0.01
cg03037030	chr6: 31543300	−0.03	0.84	−0.18	0.61	0.07	0.73	−0.29	0.14	0.03	0.96	−0.40	0.08
	chr6: 31543430							−0.44	0.02	−0.60	0.16	−0.41	0.07
	chr6: 31543487							−0.38	0.05	−0.48	0.28	−0.33	0.16
cg12681001	chr6: 31543541	−0.02	0.89	0.09	0.81	0.02	0.93	−0.12	0.54	−0.18	0.69	−0.17	0.47
cg21222743	chr6: 31543546	−0.36	0.03	−0.84	0.003	−0.22	0.28	−0.33	0.09	−0.18	0.69	−0.40	0.08
cg10717214	chr6: 31543558	−0.29	0.08	−0.57	0.09	−0.22	0.27	0.37	0.09	0.24	0.70	0.34	0.18
cg04425624	chr6: 31543566	−0.16	0.35	−0.34	0.33	−0.04	0.85	0.10	0.65	−0.85	0.07	0.30	0.25
cg21467614	chr6: 31543638	−0.33	0.04	−0.56	0.09	−0.22	0.27
cg08553327	chr6: 31543647	−0.24	0.15	−0.37	0.30	−0.13	0.53
cg26729380	chr6: 31543655	−0.37	0.03	−0.51	0.13	−0.26	0.20
cg10650821	chr6: 31543686	−0.16	0.35	0.03	0.93	−0.24	0.22
	chr6: 31544695							0.02	0.93	−0.25	0.59	0.21	0.37
	chr6: 31544752							0.06	0.77	0.65	0.11	−0.06	0.79
	chr6: 31544800							0.27	0.18	0.28	0.55	0.05	0.82
	chr6: 31544822							0.18	0.36	0.36	0.43	0.15	0.53
	chr6: 31544848							−0.07	0.72	−0.11	0.82	−0.33	0.16
cg01360627	chr6: 31544931	−0.05	0.79	−0.21	0.57	−0.09	0.67	0.16	0.44	0.04	0.92	0.05	0.85
cg23384708	chr6: 31544934	0.16	0.35	0.31	0.38	0.06	0.77	0.29	0.14	0.64	0.12	0.13	0.58
cg20477259	chr6: 31544960	0.07	0.69	0.08	0.82	0.01	0.96	0.25	0.21	0.36	0.43	0.13	0.57
	chr6: 31545253							0.09	0.67	−0.29	0.53	0.22	0.34
	chr6: 31545258							0.01	0.95	0.33	0.48	−0.12	0.62
	chr6: 31545267							0.16	0.43	0.17	0.72	0.20	0.39
cg15989608	chr6: 31545322	0.04	0.80	−0.26	0.47	0.05	0.81	0.10	0.60	0.52	0.23	0.16	0.51
cg26736341	chr6: 31545343	0.05	0.78	−0.36	0.31	0.10	0.61	0.06	0.77	0.53	0.22	−0.18	0.44
	chr6: 31545432							0.07	0.73	−0.28	0.54	0.05	0.83
cg04472685	chr6: 31545474	0.00	0.99	0.20	0.57	−0.08	0.68	−0.05	0.84	−0.44	0.39	0.07	0.80
cg19124225	chr6: 31545836	0.07	0.70	0.51	0.13	−0.20	0.32
cg02137984	chr6: 31545899	−0.03	0.87	−0.24	0.50	−0.02	0.91
cg06825478	chr6: 31546068	−0.15	0.37	−0.12	0.75	−0.22	0.27	0.31	0.12	0.38	0.40	0.30	0.20
	chr6: 31546086							0.18	0.38	0.24	0.61	0.17	0.48

underline nominal significance (P < 0.05).

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Table 2 Correlations between age and post-surgery DNAm in the TNF gene.

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