Fig. 2: Effect of antipsychotic treatment on Adra2a and Adra2c mRNA expression in rat brain cortex.

Corrected Adra2a and Adra2c mRNA expression in brain cortex of rats treated acutely (A) and chronically (B) with saline (SAL), risperidone (RIS), clozapine (CLZ), and haloperidol (HAL). Data are shown as mean ± SEM of 3−6 animals. Statistical analysis was performed by one-way ANOVA test followed by Tukey’s multiple comparison test. Statistical significance is denoted by ****p < 0.0001.