Fig. 1: Associations between PRSs for juvenile idiopathic arthritis and autism-related phenotypes, adjusted for ten genetic principal components, at all SNP p-value thresholds.

PRS polygenic risk scores, JIA juvenile idiopathic arthritis, RR relative risk, asd autism cases, SCDC social communication difficulties, coh coherence issues, repb repetitive behaviour, soc sociability temperament, Threshold SNP p-value threshold for PRS construction.