Table 2 MR analysis results assessing causal effects of rheumatoid arthritis on autism, and juvenile idiopathic arthritis on autism.

From: Genetic liability to rheumatoid arthritis on autism and autistic traits: polygenic risk score and Mendelian randomization analyses

Exposure and outcome

Method

No. of SNPs

OR (95% CI)

p-value

Rheumatoid arthritis and autism

 

IVW

40

1.01 (0.98, 1.04)

0.56

 

MR-Egger

40

1.01 (0.97, 1.05)

0.72

 

Weighted median

40

1.00 (0.96, 1.04)

0.92

Juvenile idiopathic arthritis and autism

 

IVW

6

1.00 (0.98, 1.02)

0.99

 

MR-Egger

6

1.02 (0.96, 1.08)

0.58

 

Weighted median

6

1.00 (0.98, 1.03)

0.56

  1. SNPs single nucleotide polymorphisms, OR odds ratio, (95% CIs) 95% confidence intervals, IVW inverse variance weighted method, MR-Egger Mendelian randomization Egger method.
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