Table 1 The associations between MD associated SNPs and MD through SPACOX and Cox PH model.

Depression

DCC

53

rs7231178

18

2.11 × 10⁻⁰⁹

2.23 × 10⁻⁰⁹

Mirror

movementsgaze palsy

Familial horizontal, with progressive scoliosis familial horizontal, with progressive scoliosis

rs8092490

18

2.74 × 10⁻⁰⁹

2.81 × 10⁻⁰⁹

rs146002209

18

3.74 × 10⁻⁰⁹

3.62 × 10⁻⁰⁹

SUD

BIRC6

6

rs4019436

2

2.90 × 10⁻⁰⁹

2.76 × 10⁻⁰⁹

Brain cancer

rs6543658

2

3.48 × 10⁻⁰⁹

3.30 × 10⁻⁰⁹

rs17428810

2

5.20 × 10⁻⁰⁹

4.74 × 10⁻⁰⁹

FOXP2

20

rs10228494

7

6.58 × 10⁻¹⁰

6.16 × 10⁻¹⁰

Childhood

apraxia of speechspeech and communication disorders

rs10262103

7

1.23 × 10⁻⁰⁹

1.14 × 10⁻⁰⁹

rs71149745

7

1.63 × 10⁻⁰⁹

1.54 × 10⁻⁰⁹

SEMA6D

6

rs281296

15

7.59 × 10⁻⁰⁹

7.21 × 10⁻⁰⁹

Kallmann syndrome

rs281287

15

7.81 × 10⁻⁰⁹

7.36 × 10⁻⁰⁹

rs1025143

15

1.01 × 10⁻⁰⁸

9.60 × 10⁻⁰⁹

CELF4

2

rs1941955

18

8.85 × 10⁻¹⁰

8.56 × 10⁻¹⁰

Dysgraphia and

speechcommunication di sorders

rs11663050

18

5.43 × 10⁻⁰⁹

5.26 × 10⁻⁰⁹

XK

1

rs10228494

7

6.58 × 10⁻¹⁰

6.16 × 10⁻¹⁰

McLeod syndrome

MD

ZNF684

1

rs139813674

1

8.39 × 10⁻⁰⁹

3.40 × 10⁻⁰⁹

Herpes simplex virus 1 infection