Table 2 ALE clusters significant after cluster-level FWE correction for multiple comparisons.

From: A coordinate-based meta-analysis of white matter alterations in patients with alcohol use disorder

  

Peak voxel coordinates (MNI)

     

Cluster #

Anatomical labela

x

y

z

ALE (*10−2)b

Cluster size (mm³)

Center of mass (x, y, z)

Contributing studies (%)c

Fail-Safe N(%)c

1

I Fornix

0

−8

16

2.84

2 200

−1, −4.4, 16.9

8 (44.4)

12 (66.6)

 

I Corpus Callosum

0

6

22

2.24

    
 

L Fornix

−4

−16

12

1.78

    
 

L Fornix

−6

−20

14

1.75

    

2

R Corpus Callosum

6

−18

28

2.23

1 776

10.1, −21, 29.4

7 (38.8)

51 (283.3)

 

R Cingulum

10

−24

26

2.19

    
 

R Corpus Callosum

20

−24

36

1.53

    

3

R Internal Capsule

16

−12

−8

2.10

1 064

18.8, −16.2, −8.6

5 (27.7)

6 (33.3)

 

R Internal Capsule

20

−18

−8

2.01

    

4

R Cingulum

10

28

−8

2.11

848

7.9, 27.4, −5.7

4 (22.2)

1 (5.5)

 

R Corpus Callosum

4

26

0

1.77

    
  1. I interhemispheric, L left hemisphere, R right hemisphere, x, y, z coordinates provided in MNI space.
  2. aAnatomical labeling according to the tractography-based atlas of human brain connections (Catani et al., 2008), as implemented in MRIcroGL (v1.2.20210317, https://www.mccauslandcenter.sc.edu/mricrogl).
  3. bMaximum ALE value observed in the cluster.
  4. cRatio to the number of included experiments.
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