Table 1 Demographic and clinical characteristics (Data are n (%) or mean (SD)).

From: ATAD3B and SKIL polymorphisms associated with antipsychotic-induced QTc interval change in patients with schizophrenia: a genome-wide association study

 

Risperidone

Olanzapine

Quetiapine

Aripiprazole

Ziprasidone

Perphenazine

Haloperidol

F/χ2

P

 

n = 354

n = 356

n = 333

n = 340

n = 339

n = 170

n = 148

  

Age (years)

30.85 (7.95)

30.23 (7.90)

30.89 (7.76)

31.31 (7.66)

30.48 (7.86)

32.07 (7.83)

33.47 (7.46)

3.926

0.001

Sex

       

15.493

0.017

Male

212 (59.9%)

183 (51.4%)

155 (46.5%)

168 (49.4%)

173 (51.0%)

81 (47.6)

71 (48.0%)

  

Female

142 (40.1%)

173 (48.6%)

178 (53.5%)

172 (50.6%)

166 (49.0%)

89 (52.4%)

77 (52.0%)

  

First episode

102 (28.8%)

95 (26.7%)

82 (24.6%)

96 (28.2%)

90 (26.5%)

39 (22.9%)

33 (22.3%)

4.541

0.604

CHL-equivalent dose at Endpoint (mg/day)

270.68 (103.85)

506.88 (205.50)

442.57 (165.99)

429.41 (249.52)

387.83 (200.44)

253.59 (132.67)

503.97 (274.11)

71.501

<0.001

Course of schizophrenia (month)

75.48 (68.14)

78.38 (70.76)

83.09 (73.57)

76.86 (68.56)

73.03 (67.29)

90.14 (76.82)

89.61 (68.76)

2.070

0.054

Baseline QTc (ms)

405.24 (25.92)

403.71 (23.55)

406.63 (27.51)

405.11 (25.12)

404.07 (25.09)

405.82 (25.91)

404.96 (27.93)

0.482

0.822

  1. CHL chlorpromazine.