Fig. 3: Significant changes exhibited in abundance and fatty acid composition of 1,2-Diacylglycerol (DG) in the PFC of DL macaques. | Translational Psychiatry

Fig. 3: Significant changes exhibited in abundance and fatty acid composition of 1,2-Diacylglycerol (DG) in the PFC of DL macaques.

From: Changes in gut viral and bacterial species correlate with altered 1,2-diacylglyceride levels and structure in the prefrontal cortex in a depression-like non-human primate model

Fig. 3

a–c The abundance of some lipidomic subclasses showed significantly changes with specific brain regions, displaying the increased DG in PFC, increased PA in AMY and increased GM1 in HIP in the DL group relative to HC group. The abundance of lipidomic subclasses in DL (red bars) were normalized by whose relative abundance in HC group (blue bars). d–e Analysis of fatty acyl composition of DG species by total carbon chain length and total degree of unsaturation showed variation by brain region. The carbon chain length and unsaturation degree of DG ranged congruously in three brain regions, 34–40 and 2–5, respectively. The carbon chain length of DG altered in PFC, AMY and HIP; the unsaturation of DG altered in PFC n = 6 per group. *P < 0.05, **P < 0.01, ***P < 0.001, two-sided Student t test; bars and points show mean ± SEM.

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