Table 2 Week 8 symptom improvement in the GEN and TAU treatment arms, according to HAM-D17.

From: Clinical utility of combinatorial pharmacogenomic testing in depression: A Canadian patient- and rater-blinded, randomized, controlled trial

 

Symptom improvement

Mean percentage change

Mean change

Estimate,% (SE)a

Difference

p-value

Estimate (SE)b

Difference

p-value

Per Protocol

      

GEN (N = 65)

24.41 (3.85)

1.82

0.738

5.23 (0.74)

0.13

0.901

TAU (N = 69)

22.60 (3.80)

5.10 (0.73)

Intent-to-Treat

GEN (N = 106)

22.42 (3.42)

4.61

0.350

4.70 (0.57)

0.672

0.414

TAU (N = 97)

17.80 (3.55)

4.03 (0.59)

  1. aMean percent change in HAM-D17 score from baseline to week 8.
  2. bMean absolute change in HAM-D17 score from baseline to week 8.
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