Table 1 The metabolites that are found to be relevant, as calculated by Boruta analysis, for distinguishing 22q11.2DS patients from controls, distinguishing 22q11.2DS patients with ASD from 22q11.2DS patients without ASD and distinguishing 22q11.2DS patients with an IQ score in the lowest range (IQ < 62) from 22q11.2DS patients with an IQ score in the highest range (IQ > 69).
Metabolites distinguishing 22q11.2DS patients from controls, according to Boruta analysis. | Metabolites distinguishing 22q11.2DS patients with ASD from 22q11.2DS patients without ASD, according to Boruta analysis. | Metabolites distinguishing 22q11.2DS patients with an IQ < 62 from 22q11.2DS patients with an IQ > 69, according to Boruta analysis. | |
|---|---|---|---|
(beta-1-O-[N-(2-hydroxymethyl-3-chlorophenyl)anthraniloyl]-d-glucupyranuronic acid) | Glutamyl-Tryptophan | 11′-Carboxy-alpha-tocotrienol | 3-Methoxybenzenepropanoic acid |
12-Ketodeoxycholic acid | Glutamyl-Tyrosine | 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone | DG(14:0/14:0/0:0) |
1-Methylguanosine | Glycocholic acid | 4-Methylcatechol | Diethylthiophosphate |
2′-Deoxyinosine triphosphate | Histamine | Bisnorbiotin | Hydroquinone |
3,5-Diiodothyronine | Hydroxyphenylacetylglycine | Cer(d18:0/16:0) | Hydroxyprolyl-Isoleucine |
3b,12a-Dihydroxy-5a-cholanoic acid | Hydroxyprolyl-Isoleucine | dTDP | Imidazoleacetic acid riboside |
3-Hydroxyhexadecanoylcarnitine | L-Proline | Eicosapentaenoyl Ethanolamide | Se-Methylselenocysteine |
3-Methoxytyrosine | LysoPE(0:0/18:2(9Z,12Z)) | Estrone sulfate | Tyramine |
4-Hydroxy-5-(dihydroxyphenyl)-valeric acid-O-sulfate | LysoPE(0:0/20:2(11Z,14Z)) | Galactaric acid | |
4-Hydroxybenzoic acid | N-(2-formyl-3-chlorophenyl)anthranilic acid | Hydroquinone | |
5,10-Methenyltetrahydrofolic acid | N(6)-(Octanoyl)lysine | Leukotriene B4 dimethylamide | |
5-Dodecenoic acid | N-Acetyl-L-phenylalanine | Leukotriene F4 | |
5-Hydroxyindoleacetic acid | PA(20:4(5Z,8Z,11Z,14Z)e/2:0) | L-Kynurenine | |
5-Hydroxykynurenamine | Pantetheine | ||
6-Phosphonoglucono-d-lactone | Phosphoribosyl pyrophosphate | ||
7,8-Dihydropteroic acid | Pimelylcarnitine | ||
Alpha-CEHC | Propinol adenylate | ||
Ceramide (d18:1/12:0) | Putreanine | ||
cis-2-Methylaconitate | Pyronaridine | ||
Citric acid | Quinaprilat | ||
Cortolone-3-glucuronide | Retinoyl b-glucuronide | ||
DG(15:0/16:1(9Z)/0:0) | S-Adenosylmethionine | ||
d-Glucuronic acid 1-phosphate | Sphingosine | ||
Dihydrolipoamide | Sulfate | ||
Glucosylsphingosine | Thymidine 3′,5′-cyclic monophosphate | ||
