Fig. 2: RNA editing landscape in whole blood.
From: A game changer for bipolar disorder diagnosis using RNA editing-based biomarkers
A Proportions of RNA variant types in human whole blood. A-to-G variant, indicating A-to-I editing, is disproportionately enriched. B The percentage of RNA editing sites across different intervals of editing degrees. C The proportion and numbers of A-to-I editing sites across genomic localization are shown in piechart and at the right of the gray bars. The proportion of editing sites not residing in Alu repeats is represented by black bars. D Repartition of A-to-I editing events or edited genes by chromosome or gene. Black (right y-axis): Repartition of A-to-I editing events by chromosome. Red (left y-axis): Number of edited genes by chromosome. E Distribution of Alu editing index (AEI) values in controls and depressed patients. Data are the mean ± SEM. p value of AEI index was calculated using the Wilcoxon rank-sum test.
