Table 2 Differences in magnetization transfer ratios between antipsychotic-naïve first-episode schizophrenia and healthy controls.

From: Magnetization transfer imaging alterations and its diagnostic value in antipsychotic-naïve first-episode schizophrenia

Predominant regions in clusters

T value

P valuea

Cluster size

MNI coordinates (X Y Z)

MTR values FES HCs

Precuneus_L

6.16

<0.001

332

−24 −60 28

41.6 ± 2.2 39.9 ± 2.7

Inferior parietal lobule_L

5.72

0.001

43

−28 −36 40

41.1 ± 2.3 39.3 ± 2.9

Cuneus_L

5.71

0.001

270

−18 −82 12

42.4 ± 2.3 40.8 ± 2.6

Middle temporal gyrus_L

5.68

0.001

48

−42 −58 8

40.5 ± 2.3 38.7 ± 3.0

Paracentral lobe_L

5.39

0.003

50

−14 −26 56

42.6 ± 1.8 41.3 ± 2.4

Cerebellum_L

5.27

0.005

107

−28 −60 −34

36.9 ± 2.0 35.3 ± 2.9

Thalamus_L

5.12

0.010

107

−12 −10 6

44.2 ± 1.7 43.0 ± 2.3

  1. MNI Montreal Neurologic Institute, L left, MTR magnetization transfer ratio, FES first-episode schizophrenia, HCs healthy controls.
  2. aFor peak areas of activation, multiple comparisons using the familywise error correction, with P < 0.05 considered a significant difference.
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