Table 1 Clinical and demographic characteristics of study participants.

From: Deficient prefrontal-amygdalar connectivity underlies inefficient face processing in adolescent major depressive disorder

 

Controls

MDD

Test statistic

p valuea

Age (years), range (min-max)

16.2 (1.9), 11.2–18.8

16.1 (1.4), 12.8–18.7

U = 553.5

0.425

Sex (males), No. (%)

10 (30%)

10 (33%)

χ2(1) = 0.07

0.796

Handedness (right), No. (%)

32 (97%)

28 (93%)

χ2(1) = 0.46

0.500

In-scanner movement (FD, mm)

0.16 (0.06)

0.17 (0.06)

t(61) = 0.69

0.492

CD-RISC

72.9 (10.1)

38.6 (15.6)

t(58) = 10.16

<0.001

CDI

8.4 (6.6)

29.6 (9.3)

U = 38.0

<0.001

 Anhedonia

2.3 (2.2)

10.5 (2.8)

U = 13.5

<0.001

 Negative mood

2.2 (2.0)

6.4 (2.4)

U = 88.0

<0.001

 Negative self-esteem

1.0 (1.2)

5.0 (1.7)

U = 42.0

<0.001

 Ineffectiveness

1.2 (1.2)

5.0 (1.9)

U = 54.5

<0.001

 Interpersonal problems

1.1 (1.2)

3.7 (1.5)

U = 74.5

<0.001

 Stomach

0.6 (0.6)

1.1 (0.8)

U = 301.5

0.018

RIAS IQ

104.5 (6.9)

108.0 (8.7)

t(60) = −1.75

0.079

PSS

22.4 (6.6)

28.8 (7.7)

t(57) = −3.44

0.001

SDQ

8.8 (5.3)

16.3 (5.6)

t(56) = −5.26

<0.001

WISC-IV Digitspan (forward)

8.9 (2.1)

8.8 (2.0)

t(60) = 0.32

0.747

WISC-IV Digitspan (backward)

8.6 (1.6)

9.4 (2.0)

t(60) = −1.70

0.094

WISC-IV Mosaic

57.0 (5.7)

59.0 (6.2)

t(56) = −1.27

0.208

Current Medication, No. (%)

 No medication

33 (100%)

10 (33%)

NA

NA

 SSRI

0

18 (60%)

NA

NA

 Dual-action antidepressantb

0

2 (7%)

NA

NA

 NERI

0

2 (7%)

NA

NA

 Antipsychoticc

0

2 (7%)

NA

NA

 Methylphenidate

0

2 (7%)

NA

NA

  1. Data are presented as mean (SD) if not indicated otherwise.
  2. CD-RISC Connor-Davidson Resilience Scale, CDI Children Depression Inventory, FD framewise displacement, NERI Norepinephrine reuptake inhibitor, PSS Perceived Stress Scale, RIAS Reynolds Intellectual Assessment Scales, SDQ Strength and Difficulty Questionnaire for Children, SSRI Selective serotonin reuptake inhibitor, WISC Wechsler Intelligence Scale for Children.
  3. aUncorrected p values for between-group comparisons; significance threshold p < 0.05.
  4. bSerotonin-noradrenalin reuptake inhibitor.
  5. cUsed for behavioral control.