Translational Psychiatry

Table 1 Pearson correlations among variables used in the Bayesian Network modeling.

From: Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
1. Baseline DPFC Thickness
2. Change DPFC Thickness	−0.50
3. Change Cannabis Use	−0.04	−0.17
4. Tobacco Use Baseline	−0.14	0.04	0.26
5. Change Tobacco Use	−0.03	−0.09	0.49	−0.05
6. Alcohol Use Baseline	−0.06	−0.02	0.26	0.39	0.19
7. Change Alcohol Use	0.03	−0.08	0.19	−0.13	0.28	−0.32
8. Handedness	−0.02	0.03	0.01	0.05	−0.06	0	−0.02
9. Baseline Age	−0.13	0.10	−0.03	0.04	−0.09	0.05	−0.05	−0.04
10. Cannabis PRS	−0.01	−0.01	0.10	−0.05	0.11	0.06	0.07	−0.07	−0.02
11. SES	0.06	−0.04	0.02	−0.17	−0.06	−0.04	0.08	−0.01	−0.07	0.05
12. Pubertal Development	0	0.09	0	0.03	0.05	0.17	−0.08	−0.02	0.23	−0.05	0.02
13. ADHD Baseline	0.04	−0.11	0.11	0.06	0.13	0.12	0.06	−0.01	−0.08	0.04	−0.10	−0.08
14. Change ADHD	−0.01	0.04	0	−0.04	0.03	−0.10	0.08	−0.01	0.01	0.04	0.02	0.02	−0.56
15. Childhood Trauma	−0.03	0.01	0.02	0.05	−0.01	0.01	−0.02	0.07	0.01	0.01	−0.08	−0.05	0	0.05
16. SS	−0.11	0	0.16	0.14	0.13	0.23	0.02	−0.02	−0.04	0.01	0	0.10	0.08	−0.02	−0.03
17. Change SS	0.09	−0.05	0.09	−0.08	0.07	−0.10	0.17	−0.03	−0.08	0.05	0	−0.06	0.06	0.04	0.04	−0.49

All variables were residualized for site and sex. Bold text indicates p < 0.05.
PRS Cannabis use polygenic risk score, DPFC dorsal prefrontal thickness, SES Socioeconomic Status, ADHD attention/deficit-hyperactivity disorder, SS sensation seeking, Change change in a variable from ages 14 to 19.

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