Table 2 Top 5 differentially expressed genes in caudate nucleus, putamen, and ventral striatum.
From: Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum
Entrez Gene ID | Gene name | baseMean | log2(FC) | lfcSE | Stat | P-Value | FDR |
|---|---|---|---|---|---|---|---|
Caudate nucleus | |||||||
9654 | TTLL4 | 1125.89 | 0.11 | 0.02 | 5.59 | 2.33 × 10−8 | 0.0005 |
2624 | GATA2 | 51.17 | −0.27 | 0.05 | −4.92 | 8.58 × 10−7 | 0.0091 |
25904 | CNOT10 | 695.68 | 0.06 | 0.01 | 4.84 | 1.27 × 10−6 | 0.0091 |
222256 | CDHR3 | 1483.68 | 0.19 | 0.04 | 4.75 | 1.99 × 10−6 | 0.0106 |
375611 | SLC26A5 | 63.80 | 0.28 | 0.06 | 4.62 | 3.81 × 10−6 | 0.0163 |
Putamen | |||||||
1674 | DES | 22.06 | −0.86 | 0.18 | −4.70 | 2.64 × 10−6 | 0.0486 |
2050 | EPHB4 | 118.04 | −0.19 | 0.05 | −4.19 | 2.78 × 10−5 | 0.0939 |
9144 | SYNGR2 | 499.84 | −0.20 | 0.05 | −4.19 | 2.76 × 10−5 | 0.0939 |
55741 | EDEM2 | 348.56 | −0.07 | 0.02 | −4.23 | 2.30 × 10−5 | 0.0939 |
84245 | MRI1 | 662.19 | −0.13 | 0.03 | −4.13 | 3.57 × 10−5 | 0.0939 |
Ventral striatum | |||||||
81570 | CLPB | 1188.85 | −0.11 | 0.02 | −4.56 | 5.16 × 10−6 | 0.0653 |
22899 | ARHGEF15 | 54.23 | −0.26 | 0.06 | −4.49 | 7.04 × 10−6 | 0.0653 |
55584 | CHRNA9 | 5.58 | −1.17 | 0.26 | −4.44 | 9.14 × 10−6 | 0.0653 |
100463488 | MTRNR2L10 | 4.91 | −2.07 | 0.50 | −4.16 | 3.23 × 10−5 | 0.1730 |
389161 | ANKUB1 | 30.26 | 1.35 | 0.34 | 4.02 | 5.79 × 10−5 | 0.2480 |
