Fig. 2: Treatment with Shan Zha reduced depression and anxiety-like behaviors in stressed mice.
From: Anxiolytic and antidepressants’ effect of Crataegus pinnatifida (Shan Zha): biochemical mechanisms
The effect of treatments on anxiety-like behavior in the EPM. A Mice exposed to UCMS and treated with saline spent less time in the open arms of the maze. NHT, escitalopram, Shan Zha, and Baihe treatments reduced anxiety-like behavior. n = 13–17 mice per group. *P < 0.05 vs. UCMS + saline group. Effect of treatments on depression-like behavior in the tail suspension test. B Mice exposed to UCMS and treated with saline spent more time immobile in the tail suspension test. NHT, escitalopram, and Shan Zha treatments reduced this depression-like behavior. n = 12–17 mice per group. *P < 0.05 vs. UCMS + saline group.
