Fig. 4: FACS analysis of PPs and spleen samples between two groups after FMT from RA patients or healthy controls. | Translational Psychiatry

Fig. 4: FACS analysis of PPs and spleen samples between two groups after FMT from RA patients or healthy controls.

From: Fecal microbiota transplantation from patients with rheumatoid arthritis causes depression-like behaviors in mice through abnormal T cells activation

Fig. 4

A Representative images of different expression of CD4+ T cells (% of total cells) in PPs and spleen. PPs (Student t-test: t = −4.944, P < 0.001); spleen (Student t-test: t = −2.258, P = 0.036). B Representative images of different expression of Treg cells (Foxp3+CD25+, % of CD4+ T cell) in PPs and spleen. PPs (Student t-test: t = 7.443, P < 0.001); spleen (Student t-test: t = 4.290, P < 0.001). C Representative images of different expression of Th1 cells (IFN-γ+, % of CD4+ T cell) / Th2 cells (IL-4+, % of CD4+ T cell) in PPs and spleen. PPs (Student t-test: t = −2.860, P = 0.010); spleen (Student t-test: t = −2.955, P = 0.008). D Representative images of different expression of Th17 cells (IL-17A+, % of CD4+ T cell). PPs (Student t-test: t = −0.042, P = 0.967); spleen (Student t-test: t = 0.426, P = 0.675).

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