Table 1 Epigenome-wide significant (p < 5.77E-8) QTM sites.
From: Epigenome-wide DNA methylation in obsessive-compulsive disorder
Rank p-value | CpG site | Chromosome: positiona | Nearest RefSeq curated gene (relation) | Further RefSeq annotations | p-value | effect (Δβ) | Cohen’s d | Direction of differential methylation |
|---|---|---|---|---|---|---|---|---|
1 | cg24159721 | chr1:629790 | LOC101928626 (+781 bp of start site, upstream) | MT-ND2 pseudogene 28b | 8.7E-12 | 0.032 | 1.00 | Case > Control |
2 | cg05740793 | chr11:10509544 | MT-RNR2 like 8 (+358 bp of start site, upstream) | microRNA 4485 | 1.9E-10 | 0.028 | 0.91 | Case > Control |
3 | cg20450977 | chr11:10507916 | MT-RNR2 like 8 (3’UTR) | microRNA 4485 | 3.3E-10 | 0.015 | 0.89 | Case > Control |
4 | cg16267121 | chr20:57360342 | Ribonucleic Acid Export 1 (Body) | MT-RNR2 like 3 | 8.3E-10 | 0.017 | 0.87 | Case > Control |
5 | cg15890734 | chr5:80651415 | Dihydrofolate Reductase (Body) | MT-RNR2 like 2 | 1.3E-09 | 0.015 | 0.85 | Case > Control |
6 | cg11894324 | chr1:629545 | LOC101928626 (+536 bp of start site, upstream) | MT-ND2 pseudogene 28b | 2.9E-09 | 0.023 | 0.83 | Case > Control |
7 | cg01070250 | chr1:634307 | microRNA 12136 (+1894 bp of start site, upstream) | MT-CO1 pseudogene 12b | 1.3E-08 | 0.026 | 0.79 | Case > Control |
8 | cg11330075 | chr1:632058 | microRNA 12136 (−355 bp of start site, downstream) | MT-CO1 pseudogene 12b | 4.4E-08 | 0.015 | 0.75 | Case > Control |
9 | cg15174812 | chr1:630792 | microRNA 12136 (−1621 bp of start site, downstream) | MT-CO1 pseudogene 12b | 4.6E-08 | 0.012 | 0.75 | Case > Control |
