Fig. 2: Fixel correlates of general psychopathology.

There was an age-dependent association between p-factor scores and FD in the splenium of the corpus callosum. Panel (A) shows the significant effect mapped on an axial plane, with the heatmap representing family-wise error corrected p-values ranging from 0.05 to 0.007 (brighter values are more significant). Panel (B) demonstrates the post-hoc visualization of the interaction effect, with age ranges defined by quartiles. Panel (C) displays a tractogram to further characterize the anatomy of the results; the significant ROI was used as a seed region and probabilistic tractography was used to construct the tractogram.