Table 1 Demographic and clinical characteristics of all individuals included in the meta-analysis.
From: Altered brain activation during reward anticipation in bipolar disorder
Author, year | Sample size | Male/female | Age (year) | Age at onset (year) | Illness duration (year) | Subtype | Mood state | Scale | Type of reward | NMF | PC | QS | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P/HC | P | HC | P/HC | ||||||||||
Whole-brain studies | |||||||||||||
Anna Manelis, 2018 | 34/17 | 5/29 | 7/10 | 35.07/31.41 | 19.06 | 16.01 | BD I | Dep | 2.79 (YMRS) 14.35 (HAMD) | Card guessing | 0 | NA | 13.5 |
Anup Sharma, 2016 | 24/38 | 10/14 | 17/11 | 38/39.4 | NA | 15.3 | BD I BD II | Dep | NA | Social reward | 0 | NA | 11.5 |
Claudia Hagele, 2015 | 13/54 | 8/5 | 41/13 | 36/37.7 | NA | 12.3 | BD I | Mania | 19.6 (YMRS) | Monetary incentive delay task | 1 (8%) | No | 14 |
Felix Bermpohl, 2010 | 15/26 | 8/7 | 15/11 | 38.6/38.7 | NA | 16.2 | BD I | Mania | 18.9 (YMRS) | Monetary incentive delay task | 0 | No | 12 |
Henry W. Chase, 2013 | 23/37 | 4/19 | 12/15 | 33.94/33.09 | 16.65 | 17.29 | BD I | Dep | 4.0 (YMRS) 24.7 (HAMD) | Card guessing | 0 | Yes | 14 |
Jigar Jogia, 2012 | 36/37 | 17/19 | 21/16 | 42.5/37.6 | 22.4 | 20.1 | BD I | Eut | 1.7 (YMRS) 1.8 (HAMD) | Lowa gambling task | 14 (39%) | NA | 14 |
Kristina Schwarz, 2020 | 28/110 | 12/16 | 54/56 | 34/30.4 | NA | NA | BD I | NA | 2.8 (YMRS) 8.0 (HAMD) | Monetary incentive delay task Social reward task | 0 | NA | 12.5 |
Matthias Krischner, 2019 | 25/25 | 16/9 | 16/9 | 37.3/33.1 | 21.9 | 15.4 | BD I | Eut | 4.7 (HAMD) | Monetary incentive delay task | 0 | No | 15 |
Robin Nusslock, 2012 | 21/20 | 9/12 | 8/12 | 31.53/31.56 | 18.14 | 13.39 | BD I | Eut | 2.29 (YMRS) 6.43 (HAMD) | Card guessing | 20 (95%) | Yes | 14 |
Ronny Redlich, 2015 | 33/34 | 17/16 | 16/17 | 38.12/38.59 | NA | 11.54 | BD I | Dep | 2.45 (YMRS) 22.88 (HAMD) | Card guessing | 0 | Yes | 13 |
Sarah W. Yip, 2015 | 20/20 | 12/8 | 10/10 | 22.59/22.1 | NA | NA | BD II NOS | Dep | 1.24 (YMRS) 9.24 (HAMD) | Monetary incentive delay task | 20 (100%) | Yes | 13.5 |
Sheri L. Johnson, 2019 | 24/24 | 12/12 | 13/11 | 37.04/33.92 | NA | NA | BD I | Eut | 4.03 (HAMD) | Monetary incentive delay task | 24 (100%) | No | 13.5 |
Sunny J. Dutra, 2015 | 24/25 | 9/15 | 10/15 | 31.38/29.44 | 16.33 | 14.78 | BD I | Eut | 1.5 (YMRS) | Monetary incentive delay task Social incentive delay task | 0 | Yes | 14.5 |
Stefanie Schreiter, 2016 | 20/20 | 8/12 | 12/8 | 41.6/41.45 | 26.85 | 15.5 | BD I BD II | Eut | 0.5 (YMRS) 1.85 (HAMD) | Monetary incentive delay task | 0 | No | 12 |
Xavier Caseras, 2013 | 17/20 15/20 | 6/11 6/9 | 7/13 | 42.82/42.30 40.53/42.30 | 17.57 18.92 | NA | BD I BD II | Eut | 3.17/1.80 (YMRS) 3.88/2.67 (HAMD) | Card guessing | 0 | Yes | 13.5 |
ROI studies | |||||||||||||
Bianca Kollmann, 2017 | 16/24 | 6/10 | 12/12 | 43.13/42.73 | 25.63 | NA | BD I | Eut | 0.19 (YMRS) 1.13 (HAMD) | Monetary incentive delay task | 16 (100%) | No | 10.5 |
Birgit Abler, 2008 | 12/12 | 7/7 | NA | 33.9/36.2 | NA | 12.8 | BD I | Mania | 21.8 (YMRS) | Monetary incentive delay task | 0 | NA | 11 |
Jason Smucny, 2021 | 22/49 | 15/7 | 33/16 | 21.4/20.2 | NA | 0.72 | BD I | NA | 3.2 (YMRS) | Incentivized Control Engagement | 4(18%) | NA | 9 |
Julia Linke, 2012 | 19/22 | 8/11 | 11/11 | 45/28 | 29.6 | NA | BD I | Eut | 0.9 (YMRS) 1.0 (HAMD) | Probabilistic reversal learning task | 0 | NA | 11 |
Lisa H. Berghorst, 2016 | 13/15 | 5/8 | 5/10 | 27.01/31.73 | NA | NA | BD I BD II | NA | 3.08 (YMRS) 5.62 (HAMD) | Monetary incentive delay task | 0 | Yes | 14 |
Sarah Trost, 2014 | 16/16 | 6/10 | 7/9 | 35.6/35.4 | 24.5 | 11.1 | BD I | NA | 2.3 (YMRS) | Desire-reason dilemma task | 0 | Yes | 11 |
