Fig. 2: Quantitative measurements of 3D-reconstruction. | Translational Psychiatry

Fig. 2: Quantitative measurements of 3D-reconstruction.

From: Layer III pyramidal cells in the prefrontal cortex reveal morphological changes in subjects with depression, schizophrenia, and suicide

Fig. 2

A Pyramidal cell reconstruction in 3D, with yellow lines denoting orientation and solid circles denotes the centroid of pyramidal cells. Scale bar = 20 µm. B Point pattern consisting of centroids of pyramidal cells in layer III of BA46 acquired from a biopsy. C The results of a spatial point pattern analysis of pyramidal cell centroids using the cylindrical K-function. The empirical cylindrical K-function in the directions of the three axes is shown as three curves: x-axis (solid line), y-axis (dotted line), or z-axis (dashed line). The observed point pattern is completely random only if the curves fall within the envelope (gray area). When a curve falls above the envelope, it indicates evidence of clustering; when a curve falls below the envelope, it indicates evidence of repulsiveness. If the curve in one direction is particularly high, it indicates cylinder-shaped clusters in this direction.

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