Table 2 Bidirectional effects of genetic liability to ADHD on Alzheimer’s disease.

From: Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer’s disease

  

Causal effect estimates

 
 

No. SNPs

OR

95% CI

P-value

Q p-value

ADHD on Alzheimer’s disease

IVW

10

1.00

0.98, 1.02

0.39

0.68

MR-Egger

 Intercept

10

0.99

0.99, 1.00

0.91

–

 Slope

10

1.01

0.92, 1.11

0.76

0.58

Weighted median

10

1.01

0.99,1.04

0.17

–

Alzheimer’s disease on ADHD

IVW

31

1.12

0.86, 1.44

0.37

0.10

MR-Egger

 Intercept

31

0.99

0.98, 1.01

0.97

–

 Slope

31

1.12

0.77, 1.64

0.53

0.86

Weighted median

31

1.12

0.81,1.56

0.47

–

  1. IVW inverse-variance weighted, SNP single nucleotide polymorphism, OR odds ratio, CI confidence Intervals. Results are presented per log odds ratio increase of the exposure of interest.
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