Table 4 Bidirectional effects of genetic liability to ASD on Alzheimer’s disease.
From: Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer’s disease
Causal effect estimates | |||||
|---|---|---|---|---|---|
No. SNPs | OR | 95%CI | P-value | Q p-value | |
ASD on Alzheimer’s disease | |||||
IVW | 9 | 0.99 | 0.97, 1.01 | 0.70 | 0.63 |
MR-Egger | |||||
Intercept | 9 | 1.00 | 0.99, 1.00 | 0.58 | – |
Slope | 9 | 0.97 | 0.89, 1.05 | 0.53 | 0.53 |
Weighted median | 9 | 0.99 | 0.96,1.02 | 0.66 | – |
Alzheimer’s disease on ASD | |||||
IVW | 32 | 1.19 | 0.94, 1.51 | 0.14 | 0.22 |
MR-Egger | |||||
Intercept | 32 | 1.00 | 0.99, 1.01 | 0.53 | – |
Slope | 32 | 1.10 | 0.77, 1.56 | 0.57 | 0.20 |
Weighted median | 32 | 1.17 | 0.85, 1.61 | 0.31 | – |
