Table. 6 Mediation between aerobic fitness, hippocampal formation subfield volumes, and Verbal Learning and Memory Test long-term memory scores.

Mediator	ACME	CI_low	CI_high	p	p_fdr
Tail-r	0.037	−0.089	0.190	0.520	0.776
Tail-l	0.043	−0.080	0.202	0.530	0.776
Subiculum-head-r	−0.060	−0.233	0.068	0.366	0.776
Subiculum-head-l	−0.128	−0.316	−0.009	0.020*	0.640
Subiculum-body-r	0.028	−0.043	0.133	0.486	0.776
Subiculum-body-l	0.027	−0.061	0.148	0.546	0.776
Presubiculum-head-r	−0.021	−0.207	0.145	0.790	0.832
Presubiculum-head-l	−0.051	−0.247	0.106	0.538	0.776
Parasubiculum-r	0.055	−0.057	0.198	0.346	0.776
Parasubiculum-l	−0.025	−0.132	0.047	0.558	0.776
ML-head-r	−0.071	−0.253	0.080	0.342	0.776
ML-head-l	−0.107	−0.297	0.034	0.130	0.776
HATA-r	0.052	−0.088	0.223	0.484	0.776
HATA-l	−0.023	−0.146	0.094	0.682	0.832
GCMLDG-head-r	−0.115	−0.308	0.052	0.186	0.776
GCMLDG-head-l	−0.041	−0.205	0.101	0.548	0.776
GCMLDG-body-r	0.062	−0.057	0.217	0.322	0.776
GCMLDG-body-l	0.141	0.007	0.320	0.040*	0.640
Fissure-r	0.014	−0.097	0.144	0.806	0.832
Fissure-l	0.028	−0.084	0.156	0.586	0.781
CA4-head-r	−0.101	−0.319	0.090	0.280	0.776
CA4-head-l	−0.020	−0.192	0.127	0.768	0.832
CA4-body-r	0.070	−0.065	0.248	0.330	0.776
CA4-body-l	0.130	−0.026	0.331	0.122	0.776
CA3-head-r	−0.107	−0.298	0.069	0.216	0.776
CA3-head-l	0.016	−0.099	0.150	0.780	0.832
CA3-body-r	−0.023	−0.161	0.073	0.704	0.832
CA3-body-l	0.023	−0.106	0.166	0.702	0.832
CA1-head-r	−0.124	−0.328	0.037	0.126	0.776
CA1-head-l	−0.086	−0.273	0.067	0.278	0.776
CA1-body-r	−0.055	−0.202	0.060	0.352	0.776
CA1-body-l	−0.007	−0.155	0.136	0.882	0.882

Note. The 32 mediation analyses with n = 47 are listed. The hippocampal formation subfields that were associated with aerobic fitness were used as mediators between aerobic fitness and long-term memory performance.
Significant p values (<0.05) are written in bold and marked with an asterisk.
ACME average causal mediation effect, CI_low lower confidence interval, CI_high higher confidence interval, p uncorrected p value, p_fdr fdr-corrected p value.

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