Fig. 3: Day 1: Establishment and extinction of the fear response. | Translational Psychiatry

Fig. 3: Day 1: Establishment and extinction of the fear response.

From: Stimulation of the ventromedial prefrontal cortex blocks the return of subcortically mediated fear responses

Fig. 3

Overall mean US-expectancy ratings (a), range-corrected first interval skin conductance responses (b), standardized (T-transformed) startle potentiation (c; response levels above 0 show a relative potentiation of the startle responses relative to the ITI control condition; note the relative increase in startle magnitudes probed during CS− from instructed acquisition to non-instructed extinction) and heart rate change (d) during the CS+ (blue lines) vs. the CS− (purple lines) during preacquisition, instructed fear acquisition as well as the first (extinction 1) and second half of extinction training (extinction 2). US-expectancy, skin conductance and startle potentiation are averaged across blocks of two trials, while heart rate change is averaged across all trials of a respective phase. Error bars represent the standard error of the mean.

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