Table 3 Multiple linear regression analyses of Cohen’s PSS on DNAmAA of five epigentic clocks and covariates.

From: Epigenetic aging and perceived psychological stress in old age

 

Model

Estimate

SE

p-value

 

n

7-CpG DNAmAA

1

−0.309

0.205

0.133

 

980

 

2

−0.257

0.202

0.204

 

980

 

3

−0.168

0.228

0.462

 

773

Horvath’s DNAmAA

1

−0.290

0.129

0.025

*

976

 

2

−0.269

0.129

0.037

*

976

 

3

−0.185

0.146

0.205

 

771

Hannum’s DNAmAA

1

−0.093

0.125

0.457

 

976

 

2

−0.059

0.122

0.632

 

976

 

3

0.034

0.140

0.807

 

771

PhenoAge DNAmAA

1

−0.390

0.174

0.025

*

976

 

2

−0.366

0.173

0.035

*

976

 

3

−0.121

0.186

0.518

 

771

GrimAge DNAmAA

1

−0.049

0.108

0.655

 

976

 

2

0.013

0.099

0.899

 

976

 

3

0.024

0.105

0.816

 

771

  1. Model 1: no covariates; Model 2: sex; Model 3: sex, smoking (packyears), alcohol intake (yes/no), BMI, education, and genetic ancestry.
  2. DNAmAA DNA methylation age acceleration, SE Standard Error.
  3. *p < 0.05.
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