Fig. 2: Long-lasting effects of peripubertal and late adolescent social defeat (SD) stress on exploratory activity in novel environments in WT and Gclm-KO mice. | Translational Psychiatry

Fig. 2: Long-lasting effects of peripubertal and late adolescent social defeat (SD) stress on exploratory activity in novel environments in WT and Gclm-KO mice.

From: Time of exposure to social defeat stress during childhood and adolescence and redox dysregulation on long-lasting behavioral changes, a translational study

Fig. 2

A, B open field (OF), C, D T-maze, E, F elevated-plus maze (EPM), and G, H arena used for the MK-801 test. Significant peripubertal SD effect in E and G; significant late adolescent SD effect in B, F, and H; significant genotype effect in G. Filled squares depict mice exposed to peripubertal SD that display strong reduction in social interaction. Control mice are non-stressed individuals. Data are presented with the mean and s.d. Post-hoc test: **p < 0.01, **p < 0.01, ***p < 0.001.

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