Fig. 4: The multidimensional scaling (MDS) plots of the methylation data are shown here. | Translational Psychiatry

Fig. 4: The multidimensional scaling (MDS) plots of the methylation data are shown here.

From: The phenotypic spectrum and genotype-phenotype correlations in 106 patients with variants in major autism gene CHD8

Fig. 4

In the left diagram, 11 positive test cases (pink) are displayed when plotted against affected individuals with IDDAM and a control group. These 11 cases clearly cluster within the IDDAM group and not in the control group. The other two individuals investigated with methylation analysis are displayed in the right images, with one (top-right) test sample with a possible gain of function (purple), and (bottom-right) an inconclusive test sample plotted with IDDAM signature cases (red) and reference controls (green).

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