Fig. 3: Prophylactic effects of (R)-ketamine on the expressions of proteins regulated by miR-132-5p and synaptic proteins in the PFC from CRS-exposed mice. | Translational Psychiatry

Fig. 3: Prophylactic effects of (R)-ketamine on the expressions of proteins regulated by miR-132-5p and synaptic proteins in the PFC from CRS-exposed mice.

From: A key role of miR-132-5p in the prefrontal cortex for persistent prophylactic actions of (R)-ketamine in mice

Fig. 3

A The protein expression of brain-derived neurotrophic factor (BDNF) (one way ANOVA: F2,27 = 6.985, P = 0.004). B Methyl-CpG-binding protein 2 (MeCP2) (one way ANOVA: F2,27 = 5.530, P = 0.010). C Transforming growth factor (TGF)-β1 (one way ANOVA: F2,27 = 7.523, P = 0.003). D Postsynaptic protein-95 (PSD-95) (one way ANOVA: F2,27 = 4.888, P = 0.015). E AMPA Receptor 1 (GluA1) (one way ANOVA: F2,27 = 4.825, P = 0.016) in the prefrontal cortex (PFC). The data represent mean ± SEM (n = 9–11). *P < 0.05, **P < 0.01, ***P < 0.001.

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