Fig. 1: The effect of chronic morphine on the expressions of miR-105 and pri-miR-105 in rat mPFC and primary cultured mPFC neurons. | Translational Psychiatry

Fig. 1: The effect of chronic morphine on the expressions of miR-105 and pri-miR-105 in rat mPFC and primary cultured mPFC neurons.

From: Two kinds of transcription factors mediate chronic morphine-induced decrease in miR-105 in medial prefrontal cortex of rats

Fig. 1

a The relative expression of miR-105 in rats mPFC of saline and morphine groups (n = 8 in each group, unpaired two-tailed Student’s t-test, **P = 0.0019). b The relative expression of pri-miR-105 in rats mPFC of saline and morphine groups (n = 6 in each group, unpaired two-tailed Student’s t-test, *P = 0.0268). c The relative expression of miR-105 in primary cultured mPFC neuron of saline and morphine groups (n = 3 in each group, unpaired two-tailed Student’s t-test, ***P = 0.0002). Data are presented as mean ± SEM.

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