Fig. 1: MECP2 is overexpressed in women compared to men and gender moderates MECP2 association with childhood adversities. | Translational Psychiatry

Fig. 1: MECP2 is overexpressed in women compared to men and gender moderates MECP2 association with childhood adversities.

From: Low levels of Methyl-CpG binding protein 2 are accompanied by an increased vulnerability to the negative outcomes of stress exposure during childhood in healthy women

Fig. 1

A Blood mRNA levels of methyl-CpG binding protein 2 (MECP2) are increased in women compared to men. Statistical significance was calculated by the means of non-directional Student’s t-test. $p < 0.05. Data are Mean ± standard error of the mean (SE). B Decreased expression of MECP2 is associated to more severe childhood adverse experiences, particularly in women. Statistical significance was calculated by the means of multiple linear regression. R2: 0.206 (Women); 0.003 (Men).

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